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Cyren email security in Microsoft 365: how analysis runs in your own Azure subscription without an MX change

Product Updates · Nov 11, 2026 · 3 min read

Routing your mail through a third-party gateway to get email security creates a problem most organizations quietly accept: you are sending every message in your environment through infrastructure you do not control, before you know whether it is safe. Cyren's email security for Microsoft 365 takes a different approach, and the architecture matters.

How the analysis actually runs

Cyren email security for Microsoft 365 analyses mail on a virtual machine that runs inside your own Azure subscription. It connects to Microsoft 365 through Microsoft Graph. No MX record change is required. That means your mail routing stays exactly as it is, and the analysis happens in infrastructure you own and can audit.

The reporting flows into your own Microsoft Sentinel workspace. This is not a separate portal you have to log into to see what Cyren found. Detections appear as incidents, hunting queries, and workbook data inside the SIEM your team already uses.

What Cyren is actually checking

Cyren's detections draw on the GlobalView telemetry network, which processes over a billion email, URL, and file transactions a day. The practical value of that volume is timing. Cyren detects phishing and malicious infrastructure during the staging phase, before campaigns are weaponized. By the time a message arrives in your environment referencing a domain or URL, Cyren has often already seen that infrastructure behaving badly somewhere else.

This is the detection gap that matters in email security. Most filters evaluate a URL at click time and ask whether it looks suspicious right now. Cyren's approach gives you a signal built from what that infrastructure was doing before it became a campaign. A URL can look clean at the moment it is clicked and still belong to infrastructure that was hosting phishing pages two days earlier.

What your SOC gets inside Sentinel

Cyren ships through the Microsoft Sentinel Content Hub as a packaged solution. The package includes a CCF connector, analytic rules, hunting queries, and workbooks. You are not writing detection logic from scratch.

The analytic rules surface patterns like:

• Messages from infrastructure flagged during staging
• URLs that resolve to known-malicious hosts at time of delivery
• File attachments matching threat signatures from across the GlobalView network

Hunting queries let analysts pull historical data when a campaign is identified after the fact, so you can scope backwards across your mail history without building the query yourself.

Pushing indicators to enforcement

Cyren pushes indicators into CrowdStrike Falcon and SentinelOne. This is where email telemetry becomes enforcement across the endpoint layer. A domain Cyren flags in a phishing campaign does not stay as a Sentinel alert. It becomes an indicator that your EDR platform acts on, so if that domain appears in network traffic from an endpoint, the EDR has the context to respond.

This matters operationally because email is frequently the first place malicious infrastructure appears, and endpoint telemetry is where the dwell time accumulates. Connecting those two signals with automated indicator sharing closes the gap between detection in email and enforcement at the endpoint.

Practical questions to check before you deploy

The architecture is worth verifying against your specific Microsoft 365 and Azure configuration before you start. A few things worth confirming:

• Which Azure subscription will host the analysis VM, and who has access to it
• Whether your Sentinel workspace is in the same Azure tenant as your Microsoft 365 environment
• What retention period you need for email telemetry in Sentinel, since this affects log analytics costs
• Whether your CrowdStrike or SentinelOne deployment is already connected to Sentinel for indicator ingestion, or whether that link needs to be configured separately

The Sentinel Content Hub solution handles the detection content, but the integration between your EDR platform and Sentinel determines whether the indicators Cyren generates actually reach enforcement.

If you are evaluating Cyren email security as part of a broader Microsoft 365 security review, start by confirming that your Sentinel workspace is receiving Microsoft 365 audit logs and that your EDR platform is pushing telemetry into the same workspace. Cyren's signal is most useful when it lands in an environment where other controls can act on it.

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